Accelerate your drug discovery with the world’s first digital, high-throughput, benchtop SPR system

Alto is the world’s first SPR instrument to integrate digital microfluidics (DMF) with nanotechnology-based biosensors. DMF technology enables all fluidics to be disposable, allowing for precise handling of 2µL sample volumes, crude sample compatibility and zero fluidics maintenance. Alto’s compatibility with automation for both hardware and software provides sample-in/answer-out data, industry-leading throughput, and 24+ hours of unattended run time. Every aspect of Alto is designed with user-friendliness and accessibility in mind-from the flexible 16 channel design to the intuitive data analysis platform.


Obtain publication-quality binding kinetics & affinity data on your benchtop.

OpenSPR is the world’s only benchtop surface plasmon resonance (SPR) instrument. It provides high quality, label-free interaction analysis for a fraction of the cost of existing solutions. Our unique nano-structured sensor surface uses localized SPR (LSPR) to deliver repeatable, highly sensitive kinetic data.


Maximize your productivity with fully automated, 24/7 operation of our benchtop SPR.

OpenSPR-XT is built with our cutting-edge and affordable nanotechnology biosensor platform. It has been seamlessly integrated with our robust autosampler system to allow for fully automated, 24/7 operation.

OpenSPR Sensors

OpenSPR Sensors

Optimize easily with a wide range of affordable sensor chips

Tired of expensive surface plasmon resonance sensor chips? Our nanotechnology enabled sensors are manufactured to the highest quality to ensure consistent and repeatable measurements, at half of the price of traditional sensors. We achieve less than 5% CV on all critical optical properties. Our sensors are stable in a variety of solvents, buffers and reagents. With high-quality and affordable OpenSPR Sensors, you have the freedom to run more experiments.

*Compatible with OpenSPR and OpenSPR-XT instruments

High Sensitivity Sensors

High Sensitivity Sensors provide increased sensitivity for your toughest SPR applications. The increased localized sensitivity is particularly advantageous for small molecule analysis, and can also be used to enhance the signals of other larger biomolecules

Alto™ Nicosystem™ Software

Take the guesswork out of SPR with Alto’s intuitive, flexible software

Designed for any skill level

Take the guesswork out of Surface Plasmon Resonance (SPR) with Alto’s comprehensive software - the Nicosystem™. A first of its kind, the Nicosystem provides a one-stop centralized hub for acquisition and analysis of real-time binding data, while offering you the flexibility of accessing and sharing your experiments from anywhere.

OpenSPR Software

OpenSPR Analysis Software

Enhance data acquisition with intuitive, user-friendly & robust software.

OpenSPR Software Suite

The OpenSPR software is for exclusive use with OpenSPR instruments. Designed custom for researchers, it allows for control of the instrument and fast real-time data acquisition. The OpenSPR software is included with the purchase of an OpenSPR Starter Kit.

TraceDrawer Software

TraceDrawer is the ultimate solution for real-time interaction data handling and integrates seamlessly with data produced from the OpenSPR. It can also be used with data generated from any real-time analysis tool once the data is in the appropriate format (.txt or .csv file formats). TraceDrawer can be used to post-process data (subtract references, cut, move, combine data from several experiments), evaluate kinetic constants (ka and kd), evaluate affinity constants and EC50, create reports and produce publishable figures.

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